diff --git a/patches/react-native-mmkv+2.12.2.patch b/patches/react-native-mmkv+2.12.2.patch
new file mode 100644
index 0000000000..f2d49896db
--- /dev/null
+++ b/patches/react-native-mmkv+2.12.2.patch
@@ -0,0 +1,30 @@
+diff --git a/node_modules/react-native-mmkv/src/createMMKV.ts b/node_modules/react-native-mmkv/src/createMMKV.ts
+index 15d29a0..e97a879 100644
+--- a/node_modules/react-native-mmkv/src/createMMKV.ts
++++ b/node_modules/react-native-mmkv/src/createMMKV.ts
+@@ -46,7 +46,7 @@ export const createMMKV = (config: MMKVConfiguration): NativeMMKV => {
+     }
+ 
+     // Check if we are running on-device (JSI)
+-    if (global.nativeCallSyncHook == null || MMKVModule.install == null) {
++    if (isRemoteDebuggingInChrome() || MMKVModule.install == null) {
+       throw new Error(
+         'Failed to create a new MMKV instance: React Native is not running on-device. MMKV can only be used when synchronous method invocations (JSI) are possible. If you are using a remote debugger (e.g. Chrome), switch to an on-device debugger (e.g. Flipper) instead.'
+       );
+@@ -68,3 +68,16 @@ export const createMMKV = (config: MMKVConfiguration): NativeMMKV => {
+ 
+   return global.mmkvCreateNewInstance(config);
+ };
++
++declare global {
++  const RN$Bridgeless: boolean;
++}
++
++function isRemoteDebuggingInChrome() {
++  // Remote debugging in Chrome is not supported in bridgeless
++  if ('RN$Bridgeless' in global && RN$Bridgeless === true) {
++    return false;
++  }
++
++  return __DEV__ && typeof global.nativeCallSyncHook === 'undefined';
++}
diff --git a/patches/react-native-mmkv+2.12.2.patch.md b/patches/react-native-mmkv+2.12.2.patch.md
new file mode 100644
index 0000000000..8d0a4fe5e0
--- /dev/null
+++ b/patches/react-native-mmkv+2.12.2.patch.md
@@ -0,0 +1,3 @@
+# react-native-mmkv+2.12.2.patch.md
+
+Patch of https://github.com/mrousavy/react-native-mmkv/pull/778